Engelsk definition
A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)
Engelska synonymer
Panencephalitides, Subacute Sclerosing — Sclerosing Panencephalitides, Subacute — Subacute Sclerosing Panencephalitides — SSPE — Sclerosing Panencephalitis, Subacute — Panencephalitis, Subacute Sclerosing — Inclusion Body Encephalitis, Measles — Van Bogaert's Leukoencephalitis — Van Bogaert Leukoencephalitis — Van Bogaerts Leukoencephalitis — Sclerosing Leukoencephalitis, Subacute — Leukoencephalitides, Subacute Sclerosing — Sclerosing Leukoencephalitides, Subacute — Subacute Sclerosing Leukoencephalitides — Subacute Sclerosing Leukoencephalitis — Leukoencephalitis, Subacute Sclerosing — Measles Inclusion Body Encephalitis — Encephalitis, Inclusion Body, Measles — Leukoencephalitis, Van Bogaert's — Leukoencephalitis, Van Bogaert — Leukoencephalitis, Van Bogaerts