55-kD-glykoproteiner ursprungligen definierade som differentieringsantigener på T-lymfocyter, men som också påvisats på andra celler, bl a monocyter/makrofager. CD4-antigener ingår i Ig-supergenfamilj en och deltar som hjälpelement i MHC klass II-immunsvar. På T-lymfocyter bestämmer de hjälpar/inducerarundergruppen. CD4-antigener tjänar dessutom som HIV-receptorer och binder direkt till höljeprotei net gp120.
55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.
Antigener, CD4 — CD4 receptorer — CD4 molekyl
Receptors, CD4 — Surface CD4 Receptor — CD4 Receptor, Surface — Receptors, Surface CD4 — CD4 Receptors, Surface — Surface CD4 Receptors — T4 Antigens, T-Cell — Antigens, T-Cell T4 — T4 Antigens, T Cell — T-Cell T4 Antigens — CD4 Receptor — Receptor, CD4 — CD4 Antigen — Antigen, CD4 — Antigens, CD4 — CD4 Receptors — CD4 Molecule