Svensk definition
Neurologiskt syndrom, karakteriserat av avvikelser i kognition, motorisk prestation och beteende. Det är delvis eller helt orsakat av direkta effekter av HIV-viruset i hjärnan, hellre än av en opportun infektion. Patologiska fynd inkluderar en diffus blekhet i den vita substansen, multinukleär cell encefalit och vakuolär myelopati. Kliniska manifestationer kan inkludera apati, mental slöhet och tilltagande försvagning.
Engelsk definition
A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)
Svenska synonymer
HIV-demens — AIDS-encefalopati — HIV-encefalopati — AIDS-relaterat demenskomplex — HIV-1 associerat kognitivt motor komplex
Engelska synonymer
Complex, AIDS Dementia — Dementia Complex, AIDS — HIV-Associated Cognitive Motor Complex — HIV Associated Cognitive Motor Complex — Dementia Complex, Acquired Immune Deficiency Syndrome — Acquired-Immune Deficiency Syndrome Dementia Complex — AIDS-Related Dementia Complex — AIDS Related Dementia Complex — HIV Dementia — Dementia, HIV — Dementias, HIV — HIV Dementias — Dementia Complex, AIDS-Related — Complex, AIDS-Related Dementia — Dementia Complex, AIDS Related — HIV-1-Associated Cognitive Motor Complex — HIV 1 Associated Cognitive Motor Complex — HIV-1 Cognitive and Motor Complex — HIV 1 Cognitive and Motor Complex — HIV Encephalopathy — Encephalopathies, HIV — HIV Encephalopathies — Encephalopathy, AIDS — Encephalopathy, HIV — AIDS Encephalopathy — AIDS Encephalopathies — Encephalopathies, AIDS