AIDS Dementia Complex

AIDS-demens

Svensk definition

Neurologiskt syndrom, karakteriserat av avvikelser i kognition, motorisk prestation och beteende. Det är delvis eller helt orsakat av direkta effekter av HIV-viruset i hjärnan, hellre än av en opportun infektion. Patologiska fynd inkluderar en diffus blekhet i den vita substansen, multinukleär cell encefalit och vakuolär myelopati. Kliniska manifestationer kan inkludera apati, mental slöhet och tilltagande försvagning.

Engelsk definition

A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

Svenska synonymer

HIV-demens AIDS-encefalopati HIV-encefalopati AIDS-relaterat demenskomplex HIV-1 associerat kognitivt motor komplex

Engelska synonymer

Complex, AIDS Dementia Dementia Complex, AIDS HIV-Associated Cognitive Motor Complex HIV Associated Cognitive Motor Complex Dementia Complex, Acquired Immune Deficiency Syndrome Acquired-Immune Deficiency Syndrome Dementia Complex AIDS-Related Dementia Complex AIDS Related Dementia Complex HIV Dementia Dementia, HIV Dementias, HIV HIV Dementias Dementia Complex, AIDS-Related Complex, AIDS-Related Dementia Dementia Complex, AIDS Related HIV-1-Associated Cognitive Motor Complex HIV 1 Associated Cognitive Motor Complex HIV-1 Cognitive and Motor Complex HIV 1 Cognitive and Motor Complex HIV Encephalopathy Encephalopathies, HIV HIV Encephalopathies Encephalopathy, AIDS Encephalopathy, HIV AIDS Encephalopathy AIDS Encephalopathies Encephalopathies, AIDS