Svensk definition
Autoantikroppar riktade mot cytoplasmakomponenter i polymorfonukleära leukocyter eller monocyter. De används som specifika markörer för Wegeners granulomatos och andra sjukdomar. Deras fysiopatologisk a roll är dock inte klarlagd.
Antibodies, Antineutrophil Cytoplasmic
Antineutrofila cytoplasmaantikroppar
Engelsk definition
Autoantibodies directed against cytoplasmic constituents of POLYMORPHONUCLEAR LEUKOCYTES and/or MONOCYTES. They are used as specific markers for GRANULOMATOSIS WITH POLYANGIITIS and other diseases, though their pathophysiological role is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.
Svenska synonymer
c-ANCA — p-ANCA
Engelska synonymer
ANCA — Antineutrophil Cytoplasmic Antibody — Antibody, Antineutrophil Cytoplasmic — Cytoplasmic Antibody, Antineutrophil — Neutrophil Cytoplasmic Autoantibodies — Anti-Neutrophil Cytoplasmic Antibodies — Anti Neutrophil Cytoplasmic Antibodies — Anti-Neutrophil Cytoplasmic Antibody — Anti Neutrophil Cytoplasmic Antibody — Antibody, Anti-Neutrophil Cytoplasmic — Cytoplasmic Antibody, Anti-Neutrophil — Anti-Neutrophil Cytoplasmic Autoantibody — Anti Neutrophil Cytoplasmic Autoantibody — Autoantibody, Anti-Neutrophil Cytoplasmic — Cytoplasmic Autoantibody, Anti-Neutrophil — Neutrophil Cytoplasmic Autoantibody — Autoantibody, Neutrophil Cytoplasmic — Cytoplasmic Autoantibody, Neutrophil — Anti-Neutrophil Cytoplasmic Autoantibodies — Anti Neutrophil Cytoplasmic Autoantibodies — Antineutrophil Cytoplasmic Antibodies — c-ANCA — c ANCA — p-ANCA — p ANCA