En cellyterceptor för protein-tyrosinkinas som är överrepresenterad i ett avsevärt antal adenokarcinom. Den har omfattande homologi med och kan bilda heterodimerer med EGF-receptorn (epidermal tillväxtfaktorreceptor), erbB-3-receptorn och erbB-4-receptorn. erbB-2-receptorn aktiveras vid heterodimerbildning med någon ligandbunden erbB-receptor.
A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
Receptor, erbB-2
ErbB-2 Receptor — Antigens, CD340 — CD340 Antigens — Erb-b2 Receptor Tyrosine Kinases — Erb b2 Receptor Tyrosine Kinases — Proto-Oncogene Proteins c-erbB-2 — Proto Oncogene Proteins c erbB 2 — p185(c-neu) — c-erbB-2 Protein — c erbB 2 Protein — erbB-2 Proto-Oncogene Protein — Proto-Oncogene Protein, erbB-2 — erbB 2 Proto Oncogene Protein — erbB-2 Receptor Protein-Tyrosine Kinase — erbB 2 Receptor Protein Tyrosine Kinase — neu Proto-Oncogene Protein — Proto-Oncogene Protein, neu — neu Proto Oncogene Protein — HER-2 Proto-Oncogene Protein — HER 2 Proto Oncogene Protein — Proto-Oncogene Protein, HER-2 — Proto-Oncogene Protein HER-2 — Proto Oncogene Protein HER 2 — Receptors, erbB-2 — erbB-2 Receptors — Neu Receptor — Receptor, Neu — Metastatic Lymph Node Gene 19 Protein — Proto-oncogene Protein Neu — Tyrosine Kinase-type Cell Surface Receptor HER2 — Tyrosine Kinase type Cell Surface Receptor HER2 — p185erbB2 Protein — CD340 Antigen — Oncogene Protein HER-2 — Oncogene Protein HER 2 — Proto-Oncogene Protein p185(neu)