Svensk definition
Ett heterodimert cytokin som stimulerar till produktion av interferon-gamma i T-celler och NK-celler och som även inducerar differentiering av Th1-hjälparceller. Det medverkar till initiering av cellförmedlad immunitet.
Interleukin-12
Interleukin-12
Engelsk definition
A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
Natural Killer Cell Stimulatory Factor — IL-12 — Cytotoxic Lymphocyte Maturation Factor — IL 12 — IL-12 p70 — Interleukin-12 p70 — Interleukin 12 p70 — Interleukin 12 — IL12 — Edodekin Alfa