Svensk definition
B-celltumörer som uppträder i samband med AIDS. Drabbade patienter har ofta ett framskridet sjukdomsstadium med elakartade subtyper, omfattande bl a Burkitts lymfom, storcelligt immunoblastiskt lymfom, odelad småcellslymfom och diffus storcellslymfom. Tumörerna är ofta spridda till ovanliga, extranodala ställen, och ofta föreligger kromosomavvikelser. Polyklonal B-cellsproliferation vid AIDS är sannolikt ett komplext resultat av EBV-infektion, HIV-antigenstimulering och T-cellsberoende HIV-aktivering.
Engelsk definition
B-cell lymphoid tumors that occur in association with AIDS. Patients often present with an advanced stage of disease and highly malignant subtypes including BURKITT LYMPHOMA; IMMUNOBLASTIC LARGE-CELL LYMPHOMA; PRIMARY EFFUSION LYMPHOMA; and DIFFUSE, LARGE B-CELL, LYMPHOMA. The tumors are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in AIDS is a complex result of EBV infection, HIV antigenic stimulation, and T-cell-dependent HIV activation.
Svenska synonymer
Lymfom, AIDS-relaterat
Engelska synonymer
Lymphoma, AIDS Related — Lymphoma, HIV-Related — Lymphoma, HIV Related — HIV-Related Lymphoma — HIV Related Lymphoma — HIV-Related Lymphomas — Lymphomas, HIV-Related — Lymphoma, AIDS-Associated — AIDS-Associated Lymphomas — Lymphoma, AIDS Associated — Lymphomas, AIDS-Associated — AIDS-Associated Lymphoma — AIDS Associated Lymphoma — AIDS-Related Lymphoma — AIDS Related Lymphoma — AIDS-Related Lymphomas — Lymphomas, AIDS-Related