Tumor Necrosis Factor-alpha

Tumörnekrosfaktor-alfa

Engelsk definition

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

Svenska synonymer

TNF-alfa

Engelska synonymer

Tumor Necrosis Factor alpha Cachectin Cachectin-Tumor Necrosis Factor Cachectin Tumor Necrosis Factor Tumor Necrosis Factor Ligand Superfamily Member 2 Tumor Necrosis Factor TNF Superfamily, Member 2 TNFalpha TNF-alpha