En snabbt förlöpande och ofta dödlig myelinnedbrytande sjukdom i hjärnan som främst drabbar unga vuxna och barn. Till de kliniska dragen hör snabbt inträdande svaghet, krampanfall och koma. Sjukdomen kan följa på virussjukdom eller Mycoplasma pneumoniae-infektion, men oftast ses inga utlösande tillstånd. Patologisk undersökning visar påtaglig förlust av myelin kring kärlen och nekros med mikroblödningar i den vita substansen.
A fulminant and often fatal demyelinating disease of the brain which primarily affects young adults and children. Clinical features include the rapid onset of weakness, SEIZURES, and COMA. It may follow a viral illness or MYCOPLASMA PNEUMONIAE infections but in most instances there is no precipitating event. Pathologic examination reveals marked perivascular demyelination and necrosis of white matter with microhemorrhages. (Adams et al., Principles of Neurology, 6th ed, pp924-5)
Hursts sjukdom — Akut nekrotiserande encefalit — Subakut hemorragisk leukoencefalit
Acute Hemorrhagic Leukoencephalitides — Hemorrhagic Leukoencephalitides, Acute — Hemorrhagic Leukoencephalitis, Acute — Leukoencephalitides, Acute Hemorrhagic — Acute Hemorrhagic Leukoencephalitis — Acute Hemorrhagic Encephalomyelitis — Acute Hemorrhagic Encephalomyelitides — Encephalomyelitides, Acute Hemorrhagic — Encephalomyelitis, Acute Hemorrhagic — Hemorrhagic Encephalomyelitides, Acute — Hemorrhagic Encephalomyelitis, Acute — Leukoencephalitis Acuta Hemorrhagica — Hurst's Disease — Disease, Hurst's — Hursts Disease — Hurst Disease — Disease, Hurst — Hurst Syndrome — Syndrome, Hurst — Encephalomyelitis, Acute Necrotizing Hemorrhagic — Necrotizing Hemorrhagic Encephalomyelitis — Hemorrhagic Encephalomyelitis, Necrotizing — Hemorrhagic Encephalomyelitides, Necrotizing — Necrotizing Hemorrhagic Encephalomyelitides — Necrotizing Encephalomyelitis, Hemorrhagic — Encephalomyelitis, Hemorrhagic Necrotizing — Encephalomyelitides, Hemorrhagic Necrotizing — Necrotizing Encephalomyelitides, Hemorrhagic — Hemorrhagic Necrotizing Encephalomyelitis — Encephalomyelitis, Necrotizing Hemorrhagic — Encephalitis, Acute Necrotizing — Acute Necrotizing Encephalitides — Acute Necrotizing Encephalitis — Encephalitides, Acute Necrotizing — Necrotizing Encephalitides, Acute — Necrotizing Encephalitis, Acute — Leukoencephalitis, Subacute Hemorrhagic — Hemorrhagic Leukoencephalitides, Subacute — Hemorrhagic Leukoencephalitis, Subacute — Leukoencephalitides, Subacute Hemorrhagic — Subacute Hemorrhagic Leukoencephalitides — Subacute Hemorrhagic Leukoencephalitis