En 13-aminosyrapeptid avledd ur proteolytisk klyvning av adrenokortikotropiskt hormon, N-terminalsegmentet hos ACTH. ACTH (1-13) förvandlas till amid vid C-terminalen för att bilda ACTH (1-13)NH2 som i sin tur acetyleras för att bilda alpha-MSH i de sekretoriska granularcellerna. Alfa-MSH stimulerar syntes och distribution av melanin i melanocyter hos däggdjur och i melanoforer hos lägre ryggradsdjur.
A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.
Inga svenska synonymer finns.
alpha MSH — Acetylated ACTH (1-13)NH2 — alpha-Melanotropin — alpha Melanotropin — MSH, alpha — alpha Intermedin — Intermedin, alpha — alpha-Melanocyte-Stimulating Hormone — Hormone, alpha-Melanocyte-Stimulating — alpha Melanocyte Stimulating Hormone — ACTH (1-13)NH2 — (Desacetyl)alpha-MSH — DE-alpha-MSH — MSH, (Desacetyl)alpha- — Des-Acetyl MSH — MSH, Des-Acetyl — Desacetyl alpha-MSH — Desacetyl alpha MSH — alpha-MSH, Desacetyl — Desacetyl alpha-Melanocyte-Stimulating Hormone — Desacetyl alpha Melanocyte Stimulating Hormone — Hormone, Desacetyl alpha-Melanocyte-Stimulating — alpha-Melanocyte-Stimulating Hormone, Desacetyl — (Des-Acetyl)-alpha-MSH — Adrenocorticotropin (1-13)NH2 — ACTH (1-13) — ACTH(1-13)