Svensk definition
Tre aminosyrasekvensregioner (CDR1, CDR2 och CDR3) i immunglobulinets variabla del, vilka är mycket divergerande.Tillsammans bildar regionerna från de lätta och tunga immunglobulinkedjorna en yta som kompletterar antigenet. Dessa regioner finns också hos andra medlemmar av immunglobulinsuperfamiljen, som t ex T-cellreceptorer.
Engelsk definition
Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
Region, Complementarity Determining — Regions, Complementarity Determining — Hypervariable Regions, Immunoglobulin — Hypervariable Region, Immunoglobulin — Immunoglobulin Hypervariable Region — Immunoglobulin Hypervariable Regions — Region, Immunoglobulin Hypervariable — Regions, Immunoglobulin Hypervariable — Complementarity Determining Region — Complementarity-Determining Region — Complementarity-Determining Regions — Regions, Complementarity-Determining — Complementarity Determining Region 3 — Complementarity-Determining Region 3 — Complementarity-Determining Region 3s — Third Complementarity-Determining Region — Complementarity-Determining Region, Third — Complementarity-Determining Regions, Third — Third Complementarity Determining Region — Third Complementarity-Determining Regions — Complementarity Determining Region III — Complementarity Determining Region 1 — Complementarity Determining Region I — Complementarity Determining Region 2 — Complementarity Determining Region II