Svensk definition
En medlem i kaspasfamiljen som är starkt specifik för interleukin-1beta. Enzymet är av betydelse vid inflammationstillstånd och apoptos hos däggdjur. Interleukin-1beta-omvandlande enzym förkortas ofta ICE. EC 3.4.22.36
Caspase 1
Kaspas-1
Engelsk definition
A long pro-domain caspase that has specificity for the precursor form of INTERLEUKIN-1BETA. It plays a role in INFLAMMATION by catalytically converting the inactive forms of CYTOKINES such as interleukin-1beta to their active, secreted form. Caspase 1 is referred as interleukin-1beta converting enzyme and is frequently abbreviated ICE.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
CASP1 Caspase — Caspase, CASP1 — ICE Protease — IL-1 beta Convertase — beta Convertase, IL-1 — Convertase, IL-1 beta — IL 1 beta Convertase — IL-1 beta-Converting Enzyme — beta-Converting Enzyme, IL-1 — IL 1 beta Converting Enzyme — IL1BC Enzyme — Interleukin-1 Converting Enzyme — Converting Enzyme, Interleukin-1 — Interleukin 1 Converting Enzyme — Interleukin-1beta Converting Enzyme — Converting Enzyme, Interleukin-1beta — Interleukin 1beta Converting Enzyme — Procaspase-1 — Procaspase 1 — Pro-Caspase-1 — Pro Caspase 1