Receptor, IGF Type 1

IGF typ 1 receptor

Engelsk definition

A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.

Svenska synonymer

IGF-I-receptor Insulinliknande tillväxtfaktor I-receptor IGF typ 1 alfa subenhet receptor IGF typ 1 beta subenhet receptor

Engelska synonymer

Receptors, IGF-1 IGF-1 Receptors Receptors, IGF 1 IGF-1 Receptor IGF 1 Receptor Receptor, IGF-1 Receptors, Insulin-Like-Growth Factor I IGF-I Receptor IGF I Receptor Receptor, Insulin-Like Growth Factor Type 1 Receptor, IGF-I Receptor, IGF I Receptor, Insulin-Like Growth Factor I Insulin-Like-Growth Factor I Receptor Insulin Like Growth Factor I Receptor IGF Type 1 Receptor Receptor, IGF Type 1 beta Subunit Receptor, IGF Type 1 alpha Subunit