Engelsk definition
A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The beta subunit contains an intrinsic tyrosine kinase domain.
Svenska synonymer
IGF-I-receptor — Insulinliknande tillväxtfaktor I-receptor — IGF typ 1 alfa subenhet receptor — IGF typ 1 beta subenhet receptor
Engelska synonymer
Receptors, IGF-1 — IGF-1 Receptors — Receptors, IGF 1 — IGF-1 Receptor — IGF 1 Receptor — Receptor, IGF-1 — Receptors, Insulin-Like-Growth Factor I — IGF-I Receptor — IGF I Receptor — Receptor, Insulin-Like Growth Factor Type 1 — Receptor, IGF-I — Receptor, IGF I — Receptor, Insulin-Like Growth Factor I — Insulin-Like-Growth Factor I Receptor — Insulin Like Growth Factor I Receptor — IGF Type 1 Receptor — Receptor, IGF Type 1 beta Subunit — Receptor, IGF Type 1 alpha Subunit