Reglersekvenser, viktiga för virusreplikation, belägna i båda ändar av HIV-genomet. Det långa repetitionsöverhänget (LTR) innehåller HIV-förstärkaren, promotorn och andra sekvenser. Specifika områden i LTR omfattar det negativa reglerelementet (NRE), bindningsställen för NF-kappa B och Sp1, tataboxen och "trans-acting responsive element" (TAR). Bindning av såväl cell- som virusproteiner till dessa områden styr HIV-transkriptionen.
Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.
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LTR, Human Immunodeficiency Virus — Human Immunodeficiency Virus LTR — Long Terminal Repeat, HIV — Human Immunodeficiency Virus Long Terminal Repeat — Trans-Acting Responsive Region, HIV — Trans Acting Responsive Region, HIV — HIV Trans-Acting Responsive Region — HIV Trans Acting Responsive Region — Trans-Activation Responsive Element, HIV — Trans Activation Responsive Element, HIV — Trans-Activation Responsive Region, HIV — Trans Activation Responsive Region, HIV — TAR Element, HIV — HIV TAR Element — HIV TAR Elements — TAR Elements, HIV — Sp1-Binding Site, HIV — Sp1 Binding Site, HIV — HIV Sp1-Binding Site — HIV Sp1 Binding Site — HIV Sp1-Binding Sites — Sp1-Binding Sites, HIV — HIV-1 LTR — HIV 1 LTR — LTR, HIV-1 — Negative Regulatory Element, HIV — HIV Negative Regulatory Element