Gene Products, nef

Genprodukter, nef

Svensk definition

Produkter av nef-genen (tidigare 3'-orfgenen) hos HIV. Proteinerna undertrycker virusreplikation och har negativ reglerverkan på transkriptionen. nef betyder negativ faktor.

Engelsk definition

Products of the retroviral NEF GENE. They play a role as accessory proteins that influence the rate of viral infectivity and the destruction of the host immune system. nef gene products were originally found as factors that trans-suppress viral replication and function as negative regulators of transcription. nef stands for negative factor.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

3'-orf Protein 3' orf Protein Gene Product, nef nef Gene Product nef Gene Products nef Protein