Ett cytokin som aktiverar neutrofiler och attraherar neutrofiler och T-lymfocyter. Det frisätts av flera olika celltyper, bl a monocyter, makrofager, T-lymfocyter, fibroblaster, endotelceller, samt keratinocyter genom inflammatorisk stimulering. IL-8 är en medlem av superfamiljen beta-tromboglobuliner och strukturellt besläktad med trombocytfaktor 4.
A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.
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Interleukin 8 — IL8 — Monocyte-Derived Neutrophil Chemotactic Factor — Neutrophil Activation Factor — Neutrophil-Activating Peptide, Lymphocyte-Derived — Lymphocyte-Derived Neutrophil-Activating Peptide — Neutrophil Activating Peptide, Lymphocyte Derived — Neutrophil-Activating Peptide, Monocyte-Derived — Monocyte-Derived Neutrophil-Activating Peptide — Neutrophil Activating Peptide, Monocyte Derived — Alveolar Macrophage Chemotactic Factor-I — Alveolar Macrophage Chemotactic Factor I — AMCF-I — Anionic Neutrophil-Activating Peptide — Anionic Neutrophil Activating Peptide — Neutrophil-Activating Peptide, Anionic — Peptide, Anionic Neutrophil-Activating — Chemokine CXCL8 — CXCL8, Chemokine — Chemokines, CXCL8 — CXCL8 Chemokines — Chemotactic Factor, Macrophage-Derived — Chemotactic Factor, Macrophage Derived — Macrophage-Derived Chemotactic Factor — Chemotactic Factor, Neutrophil — Neutrophil Chemotactic Factor — Chemotactic Factor, Neutrophil, Monocyte-Derived — CXCL8 Chemokine — Chemokine, CXCL8 — Granulocyte Chemotactic Peptide-Interleukin-8 — Chemotactic Peptide-Interleukin-8, Granulocyte — Granulocyte Chemotactic Peptide Interleukin 8 — IL-8