Medel som hämmar kolinesteraser. Nervtransmittersubstansen acetylkolin hydrolyseras snabbt och inaktiveras av kolinesteraser. När kolinesteraser hämmas förstärks verkan av endogent acetylkolin vid kolinerga synapser. Kolinesterashämmare har omfattande klinisk användning för sin förmåga att öka den kolinerga effekten på mag-tarmkanalen, urinblåsan, ögat och skelettmusklerna; de används också för sin effekt på hjärtat och det centrala nervsystemet.
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
Kolinesterasinhibitorer — Antikolinesterasmedel — Acetylkolinesterashämmare — Acetylkolinesterasinhibitorer
Inhibitors, Cholinesterase — Anti-Cholinesterase — Anti Cholinesterase — Anticholinesterase Agent — Agent, Anticholinesterase — Anticholinesterase Drug — Drug, Anticholinesterase — Cholinesterase Inhibitor — Inhibitor, Cholinesterase — Anticholinesterase — Anticholinesterase Agents — Agents, Anticholinesterase — Anti-Cholinesterases — Anti Cholinesterases — Anticholinesterases — Anticholinesterase Drugs — Drugs, Anticholinesterase — Acetylcholinesterase Inhibitors — Inhibitors, Acetylcholinesterase — Acetylcholinesterase Inhibitor — Inhibitor, Acetylcholinesterase — Cholinesterase Inhibitors, Irreversible — Inhibitors, Irreversible Cholinesterase — Irreversible Cholinesterase Inhibitors — Cholinesterase Inhibitors, Reversible — Inhibitors, Reversible Cholinesterase — Reversible Cholinesterase Inhibitors