En sjukdom orsakad av kraftiga neurotoxiner av protein producerade av Clostridium botulinum, vilka stör det presynaptiska frisättandet av acetylkolin vid nerv-muskelförbindelsen. Kliniska tecken är buksmärta, kräkningar, akut förlamning (också andningsförlamning), dimsyn och dubbelseende. Botulism kan delas in i flera typer (t ex matförgiftning, barnbotulism, sårbotulism m fl).
A disease caused by potent protein NEUROTOXINS produced by CLOSTRIDIUM BOTULINUM which interfere with the presynaptic release of ACETYLCHOLINE at the NEUROMUSCULAR JUNCTION. Clinical features include abdominal pain, vomiting, acute PARALYSIS (including respiratory paralysis), blurred vision, and DIPLOPIA. Botulism may be classified into several subtypes (e.g., food-borne, infant, wound, and others). (From Adams et al., Principles of Neurology, 6th ed, p1208)
Inga svenska synonymer finns.
Botulism, Toxico-Infectious — Botulism, Toxico Infectious — Toxico-Infectious Botulism — Toxico Infectious Botulism — Clostridium botulinum Infection — Clostridium botulinum Infections — Infection, Clostridium botulinum — Wound Botulism — Botulism, Wound — Wound Botulisms — Botulism, Infantile — Infantile Botulism — Infant Botulism — Botulism, Infant — Infant Botulisms — Foodborne Botulism — Botulism, Foodborne — Foodborne Botulisms