Shelterin Complex

Shelterinkomplex

Engelsk definition

A TELOMERE cap complex consisting of telomere-specific proteins in association with telomeric DNA such as telomeric dsDNA-sDNA junction. They are involved in the protection of chromosome ends and TELOMERASE regulation and play a role in CELLULAR SENESCENCE and ageing-related pathology. In general it consists of six mostly TELOMERE-BINDING PROTEINS (POT1, RAP1, TIN2, TPP1, TRF1, and TRF2).

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Complex, Shelterin Telosome Telosomes POT1-TPP1 Shelterin Complex Complex, POT1-TPP1 Shelterin POT1 TPP1 Shelterin Complex Shelterin Complex, POT1-TPP1 Telomere POT1-TPP1 Complex Complex, Telomere POT1-TPP1 POT1-TPP1 Complex, Telomere Telomere POT1 TPP1 Complex Telomere Cap Complex CST Complex Complex, CST Telomeric Capping Complex Capping Complex, Telomeric Complex, Telomeric Capping Ctc1-Stn1-Ten1 Complex Complex, Ctc1-Stn1-Ten1 Ctc1 Stn1 Ten1 Complex Telomeric Stn1-Ten1 Capping Complex Telomeric Stn1 Ten1 Capping Complex