Intercellular Adhesion Molecule-3

Intercellulär adhesionsmolekyl-3

Engelsk definition

A membrane glycoprotein and cell adhesion molecule expressed by LEUKOCYTES that contains multiple Ig-like domains. It is a ligand for LFA-1 (integrin alphaLbeta2) and integrin alpha-D/beta-2. Its interaction with LFA-1 may play a role in the PHAGOCYTOSIS of NEUTROPHILS by MACROPHAGES following APOPTOSIS.

Svenska synonymer

ICAM-3

Engelska synonymer

Intercellular Adhesion Molecule 3 Antigens, CD50 CD50 Antigens CD50 Antigen Antigen, CD50 CDw50 Antigen Antigen, CDw50 ICAM3 ICAM-3