A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences.
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Filamin — Filamin B — beta-Filamin — beta Filamin — beta-Filamins — Filamin 1-Like Protein — 1-Like Protein, Filamin — 1-Like Proteins, Filamin — Filamin 1 Like Protein — Filamin 1-Like Proteins — Protein, Filamin 1-Like — Proteins, Filamin 1-Like — Merofilamins — Merofilamin — Filamin A — Filamin 1 — alpha-Filamin — alpha Filamin — alpha-Filamins — 280 kDa Actin-Binding Protein — 280 kDa Actin Binding Protein — Filamin C — Cs, Filamin — Filamin Cs