Mannose-Binding Protein-Associated Serine Proteases

MASP-proteaser

Svensk definition

Serumserinproteaser som medverkar vid komplementaktivering. De aktiveras vid komplexbildning med mannosbindande lektin och benämns därför "Mannose-binding protein-Associated Serine Proteases" (MASP-proteaser). De klyver komplement C4 och komplement C2 till C4b2a, den klassiska aktiveringsvägens C3-konvertas (EC 3.4.21.43). EC 3.4.21.104.

Engelsk definition

Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.

Svenska synonymer
Engelska synonymer

Inga svenska synonymer finns.

MASP Proteases — Proteases, MASP — Mannose-Binding Protein-Associated Serine Protease — Mannose Binding Protein Associated Serine Protease — MBP-Associated Serine Protease — MBP Associated Serine Protease — Serine Protease, MBP-Associated — Mannan-Binding Lectin Serine Proteases — Mannan Binding Lectin Serine Proteases — MBL-Associated Serine Proteases — MBL Associated Serine Proteases — Serine Proteases, MBL-Associated — MASP — MASPs — MASP-Related Protein — MASP Related Protein — Protein, MASP-Related — MBP-Associated Serine Protease-Related Protein — MBP Associated Serine Protease Related Protein