Cytochrome-B(5) Reductase

Cytokrom-B(5)-reduktas

Engelsk definition

A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane, where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA.

Svenska synonymer

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Engelska synonymer

NADH-Cytochrome B5 Reductase B5 Reductase, NADH-Cytochrome NADH Cytochrome B5 Reductase Methemoglobin Reductase Reductase, Methemoglobin NADH-Ferrihemoglobin Reductase NADH Ferrihemoglobin Reductase Reductase, NADH-Ferrihemoglobin NADH Methemoglobin Reductase Methemoglobin Reductase, NADH Reductase, NADH Methemoglobin