T-Lymphocytes, Cytotoxic

T-lymfocyter, cytotoxiska

Engelsk definition

Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.

Svenska synonymer

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Engelska synonymer

Cytotoxic T-Lymphocyte T-Lymphocyte, Cytotoxic T Lymphocytes, Cytotoxic Cytotoxic T Cells Cytotoxic T Cell T Cell, Cytotoxic Cytotoxic T Lymphocyte Cytotoxic T Lymphocytes Lymphocyte, Cytotoxic T T Lymphocyte, Cytotoxic Cytotoxic T-Lymphocytes Cell-Mediated Lympholytic Cells Cell, Cell-Mediated Lympholytic Cell-Mediated Lympholytic Cell Cell Mediated Lympholytic Cells Lympholytic Cell, Cell-Mediated Lympholytic Cells, Cell-Mediated TC1 Cells TC1 Cell Cell, TC1 TC2 Cells TC2 Cell Cell, TC2