Genes, Intracisternal A-Particle

Gener, intracisternal A-partikel

Svensk definition

Gener i IAP-enheter (en grupp retrovirusliknande genetiska element) som kodar för virusliknande partiklar (IAP), vilka regelmässigt återfinns i tidiga embryon hos gnagare. Intracisternal avser här "cisternae" (hålrummen) i det endoplasmatiska nätverket. Under vissa förhållanden, som vid hypometylering av DNA, transkriberas generna. Transkripten påträffas i en rad olika tumörer, inkl. plasmacytom, neuroblastom, rabdomyosarkom, teratokarcinom och tjocktarmskarcinom.

Engelsk definition

Genes of IAP elements (a family of retrovirus-like genetic elements) which code for virus-like particles (IAPs) found regularly in rodent early embryos. ("Intracisternal" refers to the cisternae of the endoplasmic reticulum.) Under certain circumstances, such as DNA hypomethylation they are transcribed. Their transcripts are found in a variety of neoplasms, including plasmacytomas, neuroblastoma, rhabdomyosarcomas, teratocarcinomas, and colon carcinomas.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Genes, Intracisternal A Particle Intracisternal A-Particle Genes A-Particle Gene, Intracisternal A-Particle Genes, Intracisternal Gene, Intracisternal A-Particle Intracisternal A Particle Genes Intracisternal A-Particle Gene Gene, Intracisternal A Particle Intracisternal A-Particle Elements A-Particle Element, Intracisternal A-Particle Elements, Intracisternal Element, Intracisternal A-Particle Elements, Intracisternal A-Particle Intracisternal A Particle Elements Intracisternal A-Particle Element IAP Elements Element, IAP Elements, IAP IAP Element