Abciximab

Abciximab

Engelsk definition

A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.

Svenska synonymer

ReoPro

Engelska synonymer

c7E3 Fab Chimeric 7E3 Fab Fab, Chimeric 7E3 ReoPro Clotinab CentoRx