P-type ATPases

Engelsk definition

A highly conserved family of ATPases that facilitate the transport of lipids and cations across the plasma membrane. Structurally, they are elongated ALPHA-HELICES constituting five functionally distinct domains: three cytoplasmic domains A, N, and P which contain the catalytic sites, and two transmembrane domains. The N domain phosphorylates the P-domain at an invariant ASPARTATE residue, which, in turn, is dephosphorylated by the A domain. The phosphorylation and dephosphorylation cycles drive conformational changes in the protein between two states (E1 and E2), which allow the substrate to access the other side of the membrane.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

ATPases, P-type P type ATPases P-type ATPase ATPase, P-type P-type Adenosine Triphosphatase Adenosine Triphosphatase, P-type P type Adenosine Triphosphatase Triphosphatase, P-type Adenosine P Type Atpase Atpase, P Type Type Atpase, P E1-E2 ATPases ATPases, E1-E2 E1 E2 ATPases P-type Adenosine Triphosphatases Adenosine Triphosphatases, P-type P type Adenosine Triphosphatases Triphosphatases, P-type Adenosine Phosphorylation-type ATPases ATPases, Phosphorylation-type Phosphorylation type ATPases E1-E2 ATPase ATPase, E1-E2 E1 E2 ATPase Phosphorylation-type Adenosine Triphosphatases Adenosine Triphosphatases, Phosphorylation-type Phosphorylation type Adenosine Triphosphatases Triphosphatases, Phosphorylation-type Adenosine