B7-H1 Antigen

B7-H1 antigen

Engelsk definition

An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.

Svenska synonymer

Antigener, CD274 CD274-antigener

Engelska synonymer

Antigen, B7-H1 B7 H1 Antigen Programmed Death Ligand 1 Antigens, CD274 CD274 Antigens CD274 Antigen Antigen, CD274 B7-H1 Immune Costimulatory Protein B7 H1 Immune Costimulatory Protein B7H1 Immune Costimulatory Protein PD-L1 Costimulatory Protein Costimulatory Protein, PD-L1 PD L1 Costimulatory Protein Programmed Cell Death 1 Ligand 1 Protein PD-L1 Protein PD L1 Protein Programmed Cell Death 1 Ligand 1