Endoplasmic Reticulum-Associated Degradation

ERAD

Engelsk definition

A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.

Svenska synonymer

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Engelska synonymer

Degradation, Endoplasmic Reticulum-Associated Endoplasmic Reticulum Associated Degradation Reticulum-Associated Degradation, Endoplasmic ERAD Pathway ERAD Pathways Pathway, ERAD Pathways, ERAD