Engelsk definition
An NADPH-dependent P450 enzyme that plays an essential role in the sterol biosynthetic pathway by catalyzing the demethylation of 14-methyl sterols such as lanosterol. The enzyme acts via the repeated hydroxylation of the 14-methyl group, resulting in its stepwise conversion into an alcohol, an aldehyde and then a carboxylate, which is removed as formic acid. Sterol 14-demethylase is an unusual cytochrome P450 enzyme in that it is found in a broad variety of organisms including ANIMALS; PLANTS; FUNGI; and protozoa.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
14-Demethylase, Sterol — Sterol 14 Demethylase — Sterol 14-alpha-Demethylase — 14-alpha-Demethylase, Sterol — Sterol 14 alpha Demethylase — Lanosterol 14 alpha-Demethylase — 14 alpha-Demethylase, Lanosterol — Lanosterol 14 alpha Demethylase — CYP51 Cytochrome P-450 — CYP51 Cytochrome P 450 — Cytochrome P-450, CYP51 — P-450, CYP51 Cytochrome — Eburicol 14alpha-Demethylase — 14alpha-Demethylase, Eburicol — Eburicol 14alpha Demethylase — Obtusifoliol 14alpha-Demethylase — 14alpha-Demethylase, Obtusifoliol — Obtusifoliol 14alpha Demethylase — Cytochrome P-450 CYP51 — CYP51, Cytochrome P-450 — Cytochrome P 450 CYP51 — P-450 CYP51, Cytochrome — Sterol 14-Demethylases — 14-Demethylases, Sterol — Sterol 14 Demethylases — Eburicol 14 alpha-Demethylase — 14 alpha-Demethylase, Eburicol — Eburicol 14 alpha Demethylase