A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
Inga svenska synonymer finns.
Glioblastoma-Derived T-Cell Suppressor Factor — Glioblastoma Derived T Cell Suppressor Factor — Cartilage-Inducing Factor-B — Cartilage Inducing Factor B — Polyergin — TGF-beta2 — TGF-beta-2 — BSC-1 Cell Growth Inhibitor — BSC 1 Cell Growth Inhibitor — Suppressor Factor, T-Cell, Glioblastoma-Derived — Transforming Growth Factor beta 2 Latency Associated Peptide — TGF-beta2LAP — TGF beta2LAP — TGF-beta2 Latency-Associated Protein — Latency-Associated Protein, TGF-beta2 — TGF beta2 Latency Associated Protein