Lymphoma, Mantle-Cell

Mantelcellslymfom

Svensk definition

En sällsynt form av non-Hodgkinlymfom, med ett vanligtvis diffust mönster av både små och medelstora lymfocyter och små, delade celler. Formen utgör ca 5% av fallen av non-Hodgkinlymfom hos vuxna i USA och Europa. De flesta mantelcellslymfom är förknippade med en t(11;14)-translokering, vilket leder till förhöjt uttryck av cyklin D1-genen.

Engelsk definition

A form of non-Hodgkin lymphoma having a usually diffuse pattern with both small and medium lymphocytes and small cleaved cells. It accounts for about 5% of adult non-Hodgkin lymphomas in the United States and Europe. The majority of mantle-cell lymphomas are associated with a t(11;14) translocation resulting in overexpression of the CYCLIN D1 gene (GENES, BCL-1).

Svenska synonymer

Lymfom, mantelcell Mantelzonlymfom

Engelska synonymer

Lymphoma, Mantle Cell Lymphomas, Mantle-Cell Mantle-Cell Lymphomas Lymphocytic Lymphoma, Diffuse, Poorly Differentiated Lymphocytic Lymphoma, Diffuse, Poorly-Differentiated Mantle-Zone Lymphoma Lymphoma, Mantle-Zone Lymphomas, Mantle-Zone Mantle Zone Lymphoma Mantle-Zone Lymphomas Lymphoma, Lymphocytic, Diffuse, Intermediate Differentiated Lymphoma, Lymphocytic, Diffuse, Poorly-Differentiated Lymphoma, Small-Cell, Centrocytic Mantle-Cell Lymphoma Mantle Cell Lymphoma Diffuse Lymphocytic Lymphoma, Poorly-Differentiated Diffuse Lymphocytic Lymphoma, Poorly Differentiated Lymphoma, Centrocytic Small-Cell Centrocytic Small-Cell Lymphoma Centrocytic Small-Cell Lymphomas Lymphoma, Centrocytic Small Cell Lymphomas, Centrocytic Small-Cell Small-Cell Lymphoma, Centrocytic Small-Cell Lymphomas, Centrocytic Lymphoma, Lymphocytic, Intermediate