Proto-Oncogene Proteins c-kit

Proto-onkogenproteiner c-kit

Engelsk definition

A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Proto Oncogene Proteins c kit c-kit, Proto-Oncogene Proteins Stem Cell Factor Receptor SCF Receptor p145 c-kit c-kit, p145 p145 c kit p145(c-kit) p145c-kit p145c kit CD117 Antigen Antigens, CD117 CD117 Antigens Proto-Oncogene Protein c-kit Proto Oncogene Protein c kit c-kit, Proto-Oncogene Protein c-kit Protein c kit Protein kit Proto-Oncogene Protein Proto-Oncogene Protein, kit kit Proto Oncogene Protein Receptor, Stem Cell Factor Proto-Oncogene Protein kit Proto Oncogene Protein kit c-kit Receptor c kit Receptor