Svensk definition
Autoantikroppar som binder till receptorn för tyreoideastimulerande hormon (TSH) på sköldkörtelepitelceller. Autoantikropparna härmar TSH, vilket leder till okontrollerad produktion av sköldkörtelhormon, typisk för Graves sjukdom.
Immunoglobulins, Thyroid-Stimulating
Immunglobuliner, tyreoideastimulerande
Engelsk definition
Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE.
Svenska synonymer
Tyreoideastimulerande immunoglobuliner
Engelska synonymer
Antibodies, Thyroid-Stimulating — Ig Thyroid Stimulating — Thyroid Stimulating, Ig — Thyroid-Stimulating Autoantibody — Autoantibody, Thyroid-Stimulating — Thyroid Stimulating Autoantibody — Immunoglobulin, Thyroid-Stimulating — Immunoglobulin, Thyroid Stimulating — Thyroid-Stimulating Immunoglobulin — Thyroid Stimulating Immunoglobulin — Thyroid-Stimulating Immunoglobulins — Thyroid Stimulating Immunoglobulins — Thyroid-Stimulating Autoantibodies — Thyroid Stimulating Autoantibodies — Thyroid Stimulating Antibody — Antibody, Thyroid Stimulating — Stimulating Antibody, Thyroid — Thyroid-Stimulating Antibodies — Thyroid Stimulating Antibodies