Serinproteas med verkan på iC3b (inaktiverat komplement 3b) så att detta klyvs i C3c och C3dg med hjälp av ett trypsinliknande proteolytiskt enzym. Komplementfaktor I kallades tidigare KAF, C3bINF eller enzym 3b-inaktivator. EC 3.4.21.45.
A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator.
Inga svenska synonymer finns.
C4b-C3b-INA — C4b C3b INA — C3b Inactivator — Inactivator, C3b — C4bC3bINA — Complement C4b-C3b Inactivator — C4b-C3b Inactivator, Complement — Complement C4b C3b Inactivator — Inactivator, Complement C4b-C3b — C3b-C4b Inactivator — C3b C4b Inactivator — Inactivator, C3b-C4b — Complement 3b-Complement 4b Inactivator — Complement 3b Complement 4b Inactivator