Cadherins

Kadheriner

Svensk definition

En grupp funktionellt likaratade glykoproteiner som ansvarar för den kalciumberoende cell-till-cell-vidhäftningen. De delas in i underklasserna E-, P- och N-kadheriner, med distinkt immunologisk speci ficitet och fördelning i vävnaderna. De åstadkommer celladhesion via en homofil mekanism. Dessa föreningar har betydelse för uppbyggnaden av vävnader och hela kroppen.

Engelsk definition

Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Cadherin Liver Cell Adhesion Molecule Liver Cell Adhesion Molecules P-Cadherins P Cadherins Cadherin-3 Cadherin 3 Placental Cadherins Cadherins, Placental P-Cadherin P Cadherin E-Cadherins E Cadherins Cadherin-1 Cadherin 1 Epithelial-Cadherin Epithelial Cadherin E-Cadherin E Cadherin Uvomorulin Epithelial-Cadherins Epithelial Cadherins N-Cadherins N Cadherins Cadherin-2 Cadherin 2 N-Cadherin N Cadherin Neural Cadherins Cadherins, Neural Neural Cadherin Cadherin, Neural