Flerkärniga massor av ett flertal sammansmälta celler, ofta förknippade med virusinfektioner. I AIDS uppkommer de när HIVs höljeglykoprotein binder till CD4-antigenet på icke-infekterade T4-celler intill varandra. Det uppkomna syncytiet leder till celldöd och kan förklara virusets cellförstörande effekt.
Multinucleated masses produced by the fusion of many cells; often associated with viral infections. In AIDS, they are induced when the envelope glycoprotein of the HIV virus binds to the CD4 antigen of uninfected neighboring T4 cells. The resulting syncytium leads to cell death and thus may account for the cytopathic effect of the virus.
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Cell, Giant — Cells, Giant — Giant Cell — Syncytium — Polykaryocytes — Polykaryocyte — Syncytia — Giant Cells, Multinucleated — Cell, Multinucleated Giant — Cells, Multinucleated Giant — Giant Cell, Multinucleated — Multinucleated Giant Cell — Multinucleated Giant Cells