A secreted KAZAL MOTIF-containing serine peptidase inhibitor that inhibits TRYPSIN. It is a protein composed of 56 amino acid residues and is different in amino acid composition and physiological activity from the Kunitz bovine pancreatic trypsin inhibitor (APROTININ). It protects against the trypsin-mediated premature activation of ENZYME PRECURSORS in the PANCREAS. Mutations in the SPINK1 gene are associated with CHRONIC PANCREATITIS.
Trypsinhämmare, Kazal pankreas — Trypsininhibitor, Kazal pankreas
Serine Protease Inhibitor Kazal-Type 1 — Serine Protease Inhibitor Kazal Type 1 — Pancreatic Secretory Trypsin Inhibitor — SPINK1 — Trypsin Inhibitor, Pancreatic Secretory — Trypsin Inhibitor Kazal Pancreatic — Pancreatic Trypsin Secretory Inhibitor, Kazal — Inhibitor, Tumor-Associated Trypsin — Trypsin Inhibitor, Tumor-Associated — Trypsin Inhibitor, Tumor Associated — Tumor-Associated Trypsin Inhibitor — Tumor Associated Trypsin Inhibitor — Acidic Pancreatic Trypsin Inhibitor — Pancreatic Secretory Trypsin Inhibitor, Kazal — Serine Peptidase Inhibitor, Kazal-Type 1 — Serine Peptidase Inhibitor, Kazal Type 1 — Kazal Pancreatic Trypsin Inhibitor