Transglutaminases

Transglutaminaser

Engelsk definition

Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.

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Engelska synonymer

Protein-Glutamine gamma-Glutamyltransferases Protein Glutamine gamma Glutamyltransferases gamma-Glutamyltransferases, Protein-Glutamine Glutaminyl-Peptide Gamma-Glutamyltransferases Gamma-Glutamyltransferases, Glutaminyl-Peptide Glutaminyl Peptide Gamma Glutamyltransferases Transglutaminase