Antigenbindande enheter bestående av en komplett lätt kedja och ungefär en halv tung kedja, hoplänkade med disulfidbindningar. Fab innehåller den antigenbindande plats som är en del av det variabla området på immunglobulinmolekylen.
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Immunoglobuliner, Fab
Fab Fragments, Immunoglobulin — Fab Fragments — Fab Fragment — Fragment, Fab — Immunoglobulin Fab Fragment — Fab Fragment, Immunoglobulin — Fab Immunoglobulin Fragments — Immunoglobulin Fragments, Fab — Immunoglobulins, Fab Fragment — Fab Fragment Immunoglobulins — Fragment Immunoglobulins, Fab — Ig Fab Fragments — Immunoglobulins, Fab