Svensk definition
Läkemedel som selektivt binder till, men inte aktiverar histamin H2-receptorer, och därmed blockerar verkan av histamin. Deras viktigaste kliniska effekt är att de hämmar syrautsöndring vid behandling av magsår. De kan även påverka glatt muskulatur. Vissa av medlen i denna klass har kraftig effekt på det centrala nervsystemet, men dessa verkningsmekanismer är inte klarlagda.
Engelsk definition
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
Svenska synonymer
Histamin H2-antagonister
Engelska synonymer
H2 Antagonists, Histamine — H2 Receptor Blockaders — Blockaders, H2 Receptor — Histamine H2 Antagonist — Antagonist, Histamine H2 — H2 Antagonist, Histamine — H2 Receptor Blockader — Blockader, H2 Receptor — Receptor Blockader, H2 — Receptor Blockaders, H2 — Blockaders, Histamine H2 Receptor — Histamine H2 Receptor Blockader — Antihistaminics, H2 — H2 Antihistaminics — Receptor Antagonists, Histamine H2 — Histamine H2 Receptor Antagonists — Antagonists, Histamine H2 — Histamine H2 Blockers — Blockers, Histamine H2 — H2 Blockers, Histamine — Histamine H2 Blocker — Blocker, Histamine H2 — H2 Blocker, Histamine — Histamine H2 Receptor Antagonist — Histamine H2 Receptor Blockaders