Histamine H2 Antagonists

Histamin H2-blockerare

Svensk definition

Läkemedel som selektivt binder till, men inte aktiverar histamin H2-receptorer, och därmed blockerar verkan av histamin. Deras viktigaste kliniska effekt är att de hämmar syrautsöndring vid behandling av magsår. De kan även påverka glatt muskulatur. Vissa av medlen i denna klass har kraftig effekt på det centrala nervsystemet, men dessa verkningsmekanismer är inte klarlagda.

Engelsk definition

Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.

Svenska synonymer

Histamin H2-antagonister

Engelska synonymer

H2 Antagonists, Histamine H2 Receptor Blockaders Blockaders, H2 Receptor Histamine H2 Antagonist Antagonist, Histamine H2 H2 Antagonist, Histamine H2 Receptor Blockader Blockader, H2 Receptor Receptor Blockader, H2 Receptor Blockaders, H2 Blockaders, Histamine H2 Receptor Histamine H2 Receptor Blockader Antihistaminics, H2 H2 Antihistaminics Receptor Antagonists, Histamine H2 Histamine H2 Receptor Antagonists Antagonists, Histamine H2 Histamine H2 Blockers Blockers, Histamine H2 H2 Blockers, Histamine Histamine H2 Blocker Blocker, Histamine H2 H2 Blocker, Histamine Histamine H2 Receptor Antagonist Histamine H2 Receptor Blockaders