Gamma Secretase Inhibitors and Modulators

Gammasekretashämmare och modulatorer

Engelsk definition

Agents that suppress GAMMA-SECRETASE by inhibiting or modulating its activities. Targeted enzymatic activities include its involvement in accumulation of toxic AMYLOID BETA-PEPTIDES (e.g., Aß42) in ALZHEIMER DISEASE and activation of NOTCH RECEPTOR mediated SIGNAL PATHWAYS in certain cancer types.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

GS Inhibitors and Modulators — Gamma Secretase Modulators — Secretase Modulators, Gamma — GS Modulators — Gamma Secretase Inhibitors — Secretase Inhibitors, Gamma — GS Inhibitors