Protein-Arginine Deiminase Type 1

Engelsk definition

A peptidylarginine deiminase isoenzyme. It is a post-translational modification enzyme that catalyzes the conversion of protein-bound ARGININE residues to CITRULLINE residues in a CALCIUM ion-dependent manner. It functions within the epidermis, targeting INTERMEDIATE FILAMENTS; KERATINS; and filaggrin for CITRULLINATION to promote epidermal cornification.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Peptidyl Arginine Deiminase Type I — Protein Arginine Deiminase Type 1 — Protein Arginine Deiminase Type I — PAD Type I — Peptidylarginine Deiminase I — Protein Arginine Deiminase 1 — Peptidylarginine Deiminase Type 1 — PADI1 Protein — Peptidylarginine Deiminase Type I — Peptidyl Arginine Deiminase Type 1 — Protein-Arginine Deiminase Type I