A multiprotein complex that functions as a peptide hydrolase, or isopeptidase to cleave NEDD8 PROTEIN from the CULLIN and UBIQUITIN-PROTEIN LIGASES, controlling the activity of the ligases. It is highly conserved in eukaryotes and typically consists of 8 subunits (CSN 1-8 proteins). The COP9 signalosome was originally identified in plants, where it controls gene transcription in response to light.
Inga svenska synonymer finns.
Signalosome Complex, COP9 — COP9 Signalosome (CSN) — COP9 Signalsome — Signalsome, COP9 — Constitutive Photomorphogenesis 9 Signalsome — Constitutive Photomorphogenesis 9 Signalosome — COP9 Signalosome Subunit 1 — G Protein Pathway Suppressor 1 — COP9 Signalosome Subunit 2 — COP9 Signalosome Subunit 3 — Signalosome Subunit 3 — Subunit 3, Signalosome — FUSCA Protein 11 — Sgn3 — COP9 Signalosome Subunit 4 — COP9 Signalosome Subunit 5 — COP9 Signalosome Subunit 6 — COP9 Signalosome Subunit 7A — COP9 Signalosome Subunit 7B — COP9 Signalosome Subunit 8