Tartrate-Resistant Acid Phosphatase

Tartrat-resistent surt fosfatas

Engelsk definition

One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.

Svenska synonymer

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Engelska synonymer

Acid Phosphatase, Tartrate-Resistant Phosphatase, Tartrate-Resistant Acid Tartrate Resistant Acid Phosphatase TRAcP TRAP Type 5 AcPase Acid Phosphatase V Phosphatase V, Acid V, Acid Phosphatase AcPase V V, AcPase Type 5 Acid Phosphatase Tartrate-Resistant Acid Phosphatase Type 5 Tartrate Resistant Acid Phosphatase Type 5 Uteroferrin