Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE. Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME.
Inga svenska synonymer finns.
Kidney-Specific Na-K-Cl Symporter — Kidney Specific Na K Cl Symporter — Na-K-Cl Symporter, Kidney-Specific — Symporter, Kidney-Specific Na-K-Cl — BSC1 Transport Protein — Protein, BSC1 Transport — Transport Protein, BSC1 — NKCC2 Protein — Protein, NKCC2 — NKCC2 Cotransporter — Cotransporter, NKCC2 — SLC12A1 Cotransporter — Cotransporter, SLC12A1 — Bumetanide-Sensitive Sodium-(Potassium)-Chloride Cotransporter 2 — SLC12A1 Protein — Protein, SLC12A1