Cyclic Nucleotide Phosphodiesterases, Type 2

PDE2-fosfodiesteraser

Engelsk definition

A cyclic nucleotide phosphodiesterase subfamily that is activated by the binding of CYCLIC GMP to an allosteric domain found on the enzyme. Multiple enzyme variants of this subtype can be produced due to multiple alternative mRNA splicing. The subfamily is expressed in a broad variety of tissues and may play a role in mediating cross-talk between CYCLIC GMP and CYCLIC CMP pathways. Although the type 2 enzymes are classified as 3',5'-cyclic-AMP phosphodiesterases (EC 3.1.4.17), members of this class have additional specificity for CYCLIC GMP.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Cyclic GMP-Stimulated Phosphodiesterase — Cyclic GMP Stimulated Phosphodiesterase — Phosphodiesterase, Cyclic GMP-Stimulated — Cyclic Nucleotide Phosphodiesterase PDE2 Family — PDE2 Phosphodiesterase — PDE2 Phosphodiesterases — Cyclic Nucleotide Phosphodiesterases, Type 2A — cGMP-Dependent 3',5'-Cyclic Phosphodiesterase — 3',5'-Cyclic Phosphodiesterase, cGMP-Dependent — cGMP Dependent 3',5' Cyclic Phosphodiesterase — Phosphodiesterase 2A