Protein Tyrosine Phosphatase, Non-Receptor Type 22

Engelsk definition

A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Protein Tyrosine Phosphatase, Non Receptor Type 22 — PTPase Lyp — Lymphoid Phosphatase — Tyrosine Protein Phosphatase, Non-Receptor Type 22 — Tyrosine Protein Phosphatase, Non Receptor Type 22 — PTPN-22 Protein — PTPN 22 Protein — Protein-Tyrosine Phosphatase Lyp — Protein Tyrosine Phosphatase Lyp — Lyp1 PTPase — PTPase, Lyp1 — Lyp2 PTPase — PTPase, Lyp2