Transforming Growth Factor beta1


Engelsk definition

A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Transforming Growth Factor beta I TGF-beta1 Transforming Growth Factor-beta1 TGF-beta-1 TGF beta 1 Transforming Growth Factor beta 1 Latency Associated Peptide TGF-beta1 Latency-Associated Protein Latency-Associated Protein, TGF-beta1 TGF beta1 Latency Associated Protein TGF-beta1LAP TGF beta1LAP