Presenilins

Preseniliner

Engelsk definition

Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Presenilin